Synthesis of Silver Nanoparticles and their Antiproliferation against Human Lung Cancer Cells In vitro

A simple and inexpensive, single step synthesis of silver nanoparticles was achieved using sodium citrate both as a reducing and capping agent. Silver nanoparticles were synthesized by injecting sodium citrate solution into the solution of silver nitrate at high temperature. The synthetic process was carried out in aqueous solution, making the method versatile and ecofriendly. The synthesized silver nanoparticles were characterized by UV-visible absorption spectroscopy, field emission scanning electron microscopy (FE-SEM), and dynamic light scattering (DLS). Results showed that the average size of spherical silver nanoparticles was about 30 nm. The antiproliferation activities of the silver nanoparticles on human lung cancer cells were also studied in vitro.